Description Genome assembly refers to the process of taking a large number of short DNA sequences, all of which were generated by a shotgun sequencing project, and putting them back together to create a representation of the original chromosomes from which the DNA originated. In a shotgun sequencing project, all the DNA from a source (usually a single organism, anything from a bacterium to a mammal) is first fractured into millions of small pieces. These pieces are then "read" by automated sequencing machines, which can read up to 900 nucleotides or bases at a time. (The four bases are adenine, guanine, cytosine, and thymine, represented as AGCT.) A genome assembly algorithm works by taking all the pieces and aligning them to one another, and detecting all places where two of the short sequences, or reads, overlap. These overlapping reads can be merged together, and the process continues.Genome assembly is a very difficult computational problem, made more difficult because genomes contain large numbers of identical sequences, known as repeats. These repeats can be thousands of nucleotides long, and some occur in thousands of different locations, especially in the large genomes of plants and animals.
John Bolin, Halmstad Member Since August 2007 Artist Statement Hello there.
My name is John I´m 32 years old and i live in Sweden.
There are too much to be told but i will give it a try.
I have sailed the seven seas on a Trampliner, I´ve slept in the Taj Mahal, climbed mountains in Kathmandu, made love to a beautiful woman amongst the statues of Easter island and watched the stars rise over Machu Picchu.
I´m both great and not, smart and dumb, a great lover and a greater lover.